Mechanically ventilated patients are at high risk for complications. These risks include VAP, peptic ulcer disease (PUD), gastrointestinal bleeding, aspiration, venous thromboembolic events (VTE), and problems with secretion management. Evidence-based interventions can reduce the risk of these complications and reduce the occurrence of VAP. Implementing the ventilator bundle has shown to reduce VAP. The VAP prevention bundle includes: head of bed elevated 30 to 45 degrees, oral care with chlorhexidine 0.12%, peptic ulcer prophylaxis, deep vein thrombosis prophylaxis, and spontaneous waking trials and spontaneous breathing trials.

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